Invitro testing - Can they replace animal testing?.

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	Invitro testing - Can they replace animal testing?. Created by : Bindu Narayan, Product Development Manager, Care Biomedicals \| 04 08 2009 12:53:44 +0000 Industry : BiotechnologyFunctional Area : R&D(Operations) Keywords : biotechnology testing replace animal testing animal tissue culture invitro Activity: 1151 views; last activity : 07 06 2010 20:18:09 +0000 Invitro testing has emerged as new technology to determine the safety or effectiveness of a drug or ingredient. It seems a good alternative to animal testing, but is it as effective and accurate as animal testing? Can it replace animal testing?

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Well ACC techniques are a boon in clinical reaearch. Reasons include: 1. Animal usage for testing is reduced though cannot be completely avoided. 2. Provide a platform for preliminary testings of the drug so that confirmed effective drugs in the in-vitro testing can be taken further for animal testings. 3. In this way, faster testings are possible. So this technique is defintely promising. With more research it could take up the place of animal systems to a greater extent than now.

Nothin is Impossible in science...!!!!

By Agalya Priyadarshni.K, Student, P.s.G.College of Arts & science 04 29 2009 18:10:21 +0000

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Support "Yes" edit in rich text ... Submit Cancel Saving ... 1 0 yes, we can replace animal studies with in-vitro studies but there are limitations like we can not test antiepileptic effects or antipsychotic effect. all we can do it that try to reduce the use of animals for that we should knpw the 4R consept By Navnath K. Bodke, Clinical Research Associates, Anazeal Analytical and research pvt. ltd. \| 06 01 2009 15:16:11 +0000 Edit \| Delete Support \| Oppose 1 0 Yes, In-vitro testing should replace animal testing... Animal tissue culture is an emerging branch of biotechnology which has brought revolution in the field of biotechnogy. Many techniques in ATC are used for drug testing and slowly it will replace animal testing.. By Sovan Maiti, Product Development Manager, Care Biomedicals \| 04 29 2009 09:59:05 +0000 Edit \| Delete Support \| Oppose 1 0 Yes by all means In Vitro testing will replace animal testing to a great extent. It will help in saving animal life to a great extent, though the end product of In Vitro testing may differ.But it is sure tha it is of great help. By BEENA AGARWAL, Head/VP/GM-Corporate Planning/Strategy, ANADI HI TECH AGRO PVT LTD \| 04 19 2009 14:01:47 +0000 Edit \| Delete Support \| Oppose 0 0 Dear Subhan let tell you that it has been estimated that approximately, 20 million animals are being used for testing and are killed annually; about 15 million of them are used to test for medication and five million for other products. Reports have been generated to indicate that about 10 percent of these animals are not being administered with painkillers. You cannot meddle with them just because you can, even they have the right to live their own life peacefully. By Bindu Narayan, Product Development Manager, Care Biomedicals \| 04 13 2009 11:50:29 +0000 Edit \| Delete Support \| Oppose 1 0 I think very few people know about the European Centre for the Validation of Alternative Methods. They are taking efforts to prevent animal testing as it is against the health and morality of living creatures. In Vivo testing is coming up as a potential alternative to animal testing as tissue from several species, including man, can be examined. These tests should reduce the number of animal tests required for screening new drugs. By Kaushik Dutta, Product Development Manager, Biocon \| 04 13 2009 08:08:34 +0000 Edit \| Delete Support \| Oppose 0 0 According to me it should definitely replace the animal testing. There are sufficient evidence which prove that in-vitro studies are capable of providing more rapid, precise, and relevant information than do some animal studies. At this time, the primary use of in-vitro tests is in studying the toxicity and properties of drugs and chemicals. Specific properties of drugs can be identified including mutagenic and carcinogenic effects. Tissue from several species, including man, can be examined. Therefore this technique should be explored to get maximum benefit out of it and then it can definitely replace animal testing. By Bindu Narayan, Product Development Manager, Care Biomedicals \| 04 08 2009 12:53:44 +0000 Edit \| Delete Support \| Oppose	Support "No" edit in rich text ... Submit Cancel Saving ... 0 0 I agree that ATC techniques has made tremendous advances in the recent past, even chip technologies have been devised to evaluate the drug actions, however, the simulation of the entire body using these techniques is still far away at the present time. Even tissue cultures cannot fully simulate the living conditions of the animal particularly as far as the different cellular interactions are concerned. Thus I feel we still are not in a position to say that the Animal studies can be fully eliminated. By Anindya Basu, Research Scholar, NTU \| 04 29 2009 11:54:07 +0000 Edit \| Delete Support \| Oppose 0 0 I would say that it is not the correct time for the replacment of the techniques. Animal testing now is justified because it assists in discovering ways to help people and other animals for the future. Surgery on animals has assisted in developing organ transplant and open-heart surgery techniques. Animal testing has also assisted in developing vaccines against diseases like rabies, polio, measles, mumps, rubella and TB. Development of antibiotics, HIV drugs, insulin and cancer treatments depend upon animal tests. And now when other techniques are not advanced enough there is nothing wrong in animal testing. By Subhan Kanti Biswas, Product Development Manager, Biocon \| 04 13 2009 11:44:46 +0000 Edit \| Delete Support \| Oppose 0 0 In vitro testing can replace animal testing to a certain extent but the technology still needs to be worked on in terms of specificity of results. The condition in in-vitro testing is not same as in any body and this leads to uncertainity in results. Even though efforts are taken to maintain the appropriate conditions but it is not possible to introduce everything ( proteins, immunological factors, etc.) present in an animal body into artificial conditions. Therefore I feel that it will still require a lot of time to stop animal testing. By Sudhir Mittal, Product Development Manager, Biocon \| 04 13 2009 08:15:20 +0000 Edit \| Delete Support \| Oppose
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