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Industry : Pharmaceuticals Functional Area : Innovation
Activity:  8 comments  127 views  last activity : 11 24 2010 15:49:24 +0000
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Aspirin 'cuts prostate cancer risk by 30%': A tablet a day helps stop killer tumours forming

Powerful and cheap: Aspirin could protect against prostate cancer

Men who take a low dose of aspirin every day could cut their risk of developing prostate cancer by almost 30 per cent, research shows.

A 75mg tablet taken on a daily basis has a powerful protective effect against the disease, according to scientists.

The painkiller appears to work by blocking the effect of enzymes which cause inf lammation thought to be a key factor in the development of prostate cancer.

The study, by specialists at the Fred Hutchinson Cancer Research Centre in Seattle, is the latest in long line of investigations into whether aspirin can help prevent prostate tumours from forming.

It examined and compared two groups of men – 1,001 prostate cancer sufferers and 942 cancerfree volunteers of a similar age.

When the experts looked at how often men in both groups took aspirin, they found higher usage among the cancer-free volunteers.

Men who had used aspirin at any point in the previous 12 months were 21 per cent less likely to develop a tumour.

Those who had taken aspirin frequently for five years or more saw a 24 per cent decline in risk. But the biggest benef its appeared to be among those regularly taking a low daily dose of 75mg.

Among this group, the chances of developing prostate cancer dropped by 29 per cent.

Other pain-killing medications similar to aspirin, which are known as non- steroidal antiinflammatory drugs, did not have the same effect.

Nearly 32,000 cases a year are diagnosed. The risks increase with age, with men aged over 50 more likely to develop a prostate tumour, and there is also a strong genetic link. 

 

The anti-cancer effects of Aspirin are thought to occur primarily-through the direct inhibition-of enzymes called PTGS1 and PTGS2.’

Although doctors often recommend a low daily dose to heart disease patients to help thin the blood and reduce the risk of clots, some studies suggest that even taking small amounts can increase the chances of stomach bleeding.

Regular use of aspirin has already been linked to a lower risk of other types of cancers. A 2007 study at the Mayo Clinic in Minnesota found that, as well as prostate cancer, the risk of developing breast, ovarian and lung cancer was slashed by taking aspirin several times a week.

A common skin cancer was 90 per cent less likely among regular aspirin users, it found.

ASPIRIN has been found to be a wonder drug in the treatment of or lowering the risk of stroks, cancers (prostate cancer, risk of developing breast, ovarian, lung and skin cancers), pain and arthritis.

 Top Comment : George Varghese   | 08 13 2010 04:07:25 +0000
The main side effect of aspirin is on regular consumption it can cause internal bleeding, and gastroenterology problems.
 
8 comments on "ASPIRIN cuts PROSTATE CANCER risk by 30%"
  Commented by  rakeshbhatnagar, GM Projects., wig brothers india pvt.ltd.    | 11 24 2010 15:49:23 +0000
very nice and usefull information but what about the side effects of asprin.
  Commented by  s.baalu, SALES,MARKETING,FINANCE,ADMINISTRATION CONSULTANT, DASPAN INDUSTRIES LTD    | 08 17 2010 13:51:15 +0000
THANK YOU FOR THE VERY USEFUL INFORMATION IN SIMPLE TERMS.PLEASE CONTINUE.
  Commented by  R N Bhattacharyya, Freelancer, Freelancer    | 08 14 2010 15:07:55 +0000
By taking Aspirin type(75mg) medicene once daily ,for last 6 mnths, my LIPID Profile has been improved a lot. 
  Commented by  Prasanna, Quality assurance , Biocon India    | 08 13 2010 12:49:36 +0000
Thanks for the informative article suresh. And as george said regular consumption will create side effects........ 
  Commented by  nagesh rao, Freelancer, Freelancer    | 08 13 2010 06:57:01 +0000
yes no doubt that  aspirin can curtail certain  deceases &also it makes blood thin so that the blood  flow will be smooth to  the heart, hence it is prescribed regular,daily dosage for Heart Patients. Almost all scheduled medicines including certain over the counter medicines  have side effects. It is better to consult Doctor before consuming any medicine as daily dosage. Medicines r like a double edged sword one should be careful to avoid unnecessary complications,rather carried away by these researches & reports.
  Commented by  KAMAL TANDON, Sales Head, KEE PHARMA LIMITED    | 08 13 2010 06:37:35 +0000
suresh you have been doing a Saviour job by bringing forth such good simple info. for the layman.

aspirin is in many ways a life saving drug -- one of the oldest drugs in the world whose uses and effects are still being unearthed.

few years back it was discovered that aspirin prevents platelet formation by thinning the blood hence prevents arteriosclerosis thus saving people from strokes and heart attacks.
and now you bring the news of it cutting down risk of prostrate cancer -- it is a good news for all males above age 50 wherein every 4 th male is a potential case for prostrate cancer - if a simple aspirin can prevent it  it will be a boon.
moreover 75 mg taken once even for long term duration does not cause in most users problem of internal bleeding or gastro problems as the data suggests. 
  
Aspirin when it was first brought into the market in 1853 by Bayer ruled the market for more than 6 decades.  A research that conducted in 1918 suggested that it was instrumental in the high death toll of 1918 flu.  Low dose of Aspirin in take has impact for the cure migraine and other mild aches.  High dose of aspirin side to have many side effects including internal bleeding. The mortality rate is said to be 2%.  Then why go for Aspirin 
  Commented by  George Varghese, Proprietor, Jecyees    | 08 13 2010 04:07:25 +0000
Rating : +1 
The main side effect of aspirin is on regular consumption it can cause internal bleeding, and gastroenterology problems.  
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