Now, drug that kills deadly superbugs within 5 minutes

It is good news for all of us.
Thanks for sharing it , Suresh.

Thanks for sharing such valuable information Sir. Great news for the medical world! 

Hey suresh ...... good news.... next step in the medical industry. Thanks for sharing... :) 

GOOD INFORMATION THANKS FOR SHARING.

Dear Chandra Shekhar, An elaborated picture about N.gonorrhoea has been posted by you. You are talking about just one pathogen and here researchers are busy in finding out solution for several other pathogens too. In the above research, you will notice that the researchers have used MRSA (which is a real tough organism) in the study and the results are very positive. According to the detailed study, it seems that this single antibiotic will be able to kill varieties of pathogens without developing resistance.

Probable 'superbug' status for sexually-transmitted infection

When microorganism attains the ability to withstand the effects of antibiotic, they are known as antibiotic resistant microbes or drug resistant microbes. An antibiotic resistance is a stage or phase attained by a microbe via natural selection acting upon random mutation, though it can also be engineered by applying an evolutionary stress on a population. Once such kind of gene is developed, microbes gain the ability to transfer their genetic information in a horizontal fashion (between individuals) by conjugation, transduction, or transformation. Most of the antibiotic resistant genes reside on plasmids in order to ease their transfer. Microbe carrying resistance genes, are termed as multi-resistant or, informally, a “superbug”. The term antimicrobial resistance is sometimes used explicitly to encompass organisms other than bacteria.

Increase in number of multidrug resistance in gonorrhoea-causing bacteria make this sexually transmitted infection highly difficult to treat. Professor Catherine Ison, addressing at the society for General Microbiology's spring meeting in Edinburgh, pointed out that strains of Neisseria gonorrhoeae which is considered as immune to the present available treatments choice could emerge in the near future.

Also Professor Ison, from Health Protection Agency (HPA), London, depicted how few strains of gonococcal bacteria that are capable of causing disease are now showing less sensitivity to available antibiotics those are used to treat them - such as ceftriaxone and cefixime.

Gonorrhoea is considered as the second most common bacterial infection which is sexually-transmitted. It is observed that if this type of infection is left untreated, it can then lead to several diseases and complications such as pelvic inflammatory disease, ectopic pregnancy, and infertility in women. The present available and suggested treatment consists of single dose of antibiotic provided in the clinic when prescribed, such as cefixime – though Mouth and ceftriaxone – though Injection.

Professor Ison added, "Choosing an effective antibiotic can be a challenge because the organism that causes gonorrhoea is very versatile and develops resistance to antibiotics very quickly”. She briefly explained "Penicillin was in use for many years till it lost its antibacterial activity against disease causing microbes and also due to the use of number of other agents that is been used for killing of microbes. The current drugs of choice, ceftriaxone and cefixime, are still very effective but there are signs that resistance particularly to cefixime is emerging day by day and soon these drugs may not be a good drug of choice".

In general case bacterias isolated from patients are diagnosed for gonorrhoea are tested for their susceptibility to various antibiotic through antibiotic susceptibility test, in order to monitor specific blueprints of resistance at local and national stage. It is very difficult to maintain ongoing monitoring of antimicrobial resistance as first line of treatment for gonorrhoea to remain effective. "There are few new drugs available and so it is probable that the current use of a single dose may soon need to be revised and treatment over several days or with more than one antibiotic will need to be considered," Professor Ison warned. "If this problem isn't addressed then there is a real possibility that gonorrhoea will become a very difficult infection to treat," she added.

Resourced from www.harneedi.com 

its really a good news for the medical world