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By : Suresh Prasad Gupta, Freelancer, Pharmaceuticals
Industry : Pharmaceuticals Functional Area : Innovation
Activity:  4 comments  152 views  last activity : 07 18 2012 05:22:15 +0000
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Vaccine for alcoholics works by making you feel sick after one drink

 


Alcoholics can build up a strong tolerance to the effects of drink over time thanks to an enzyme in the liver. The new vaccine would disrupt this function.


Scientists have come up with a novel way to help alcoholics quit - by creating a vaccine that gives the sensation of a terrible hangover after just a few drinks.

Researchers from Chile said the it works by neutralising a group of enzymes that help the body to break down alcohol.

This group known as aldehyde dehydrogenase, helps the body to build up a tolerance to heavy nights out.

About 20 percent of the Asian population lacks this enzyme and thus experience 'such a strong reaction that it discourages consumption,' said lead researcher Juan Asenio, of Chile's Faculty of Sciences and Mathematics.


The vaccine would similarly increase nausea, an accelerated heart beat, sweating and a general feeling of 'unease'.


'With the vaccine, the desire to consume alcohol will be greatly reduced thanks to these reactions,' Mr Asenjo told Radio Cooperativa.
He added that the vaccine would specifically target liver cells and avoid having a knock-on effect on other cells.


Researchers have already successfully tested the vaccine on rats who were dependent on alcohol and got them to halve their consumption.

They will conduct further animal tests this year before launching human trials in 2012.


Mr Asenjo said they hoped the vaccine would reduce alcohol consumption by 90 to 95 per cent.

 

 
4 comments on "Vaccine for alcoholics works by making you feel sick after one drink"
  Commented by  Business Management Consultant, : I can provide you with Management Consulting & Counseling Services    | 07 18 2012 05:22:12 +0000
That's interesting to know. It just might help some people. Sometimes people need to have the will-power to quit. They can do this with therapy, counseling and family support without drugs.
  Commented by  s.baalu, Consultant, XYZ LTD    | 01 26 2011 14:04:22 +0000
Suresh thank you .
  Commented by  Rathin Deb, Resident Manager, Tower Infotech Ltd.    | 01 24 2011 10:07:19 +0000
Thanks Suresh for the information.
  Commented by  SHRIKANT MANOHAR DANKE, Consultant, Project Management Consultancy Firm    | 01 24 2011 08:50:47 +0000
It's great invention & will be useful for those people who really want to quit the habit 

of drinking.

Thanks for these useful information, Suresh.
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